Description
ADPRH (ADP-ribosylarginine hydrolase), also known as ADP-ribose-L-arginine cleaving enzyme, belongs to the ADP-ribosylglycohydrolase family. This protein catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-ribosylation cycle. unlike the rat and mouse enzymes, which require DTT for maximal activity, the human enzyme is DTT-independent. Recombinant human ADPRH protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques